Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury
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چکیده
منابع مشابه
Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury
INTRODUCTION The optimal blood glucose target following severe traumatic brain injury (TBI) must be defined. Cerebral microdialysis was used to investigate the influence of arterial blood and brain glucose on cerebral glucose, lactate, pyruvate, glutamate, and calculated indices of downstream metabolism. METHODS In twenty TBI patients, microdialysis catheters inserted in the edematous frontal...
متن کاملmM in patients with severe traumatic brain injury
Introduction: The optimal blood glucose target following severe traumatic brain injury (TBI) must be defined. Cerebral microdialysis was used to investigate the influence of arterial blood and brain glucose on cerebral glucose, lactate, pyruvate, glutamate, and calculated indices of downstream metabolism. Methods: In twenty TBI patients, microdialysis catheters inserted in the edematous frontal...
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Background: Cognitive impairment is a common complication of Severe Traumatic Brain Injury (STBI). One of cognitive problems following STBI is impaired executive functions which involve high-level cognitive processes and their dysfunction can lead to reduced quality of life. Objective: This study aims to investigate the cognitive impairment in men with STBI compared to healthy men. Materials...
متن کاملDifferential influence of arterial blood glucose on cerebral metabolism following severe traumatic brain injury
INTRODUCTION Maintaining arterial blood glucose within tight limits is beneficial in critically ill patients. Upper and lower limits of detrimental blood glucose levels must be determined. METHODS In 69 patients with severe traumatic brain injury (TBI), cerebral metabolism was monitored by assessing changes in arterial and jugular venous blood at normocarbia (partial arterial pressure of carb...
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Background and purpose: Allicin has a wide range of pharmacological functions, all of which can be demonstrated in anti-inflammatory, antioxidant, antifungal and anti-tumor activities. In this research, we investigated the neuroprotective role of allicin in the process of diffuse traumatic brain injury and its effect on interleukin levels and histological changes in rats. Materials and method...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2010
ISSN: 1364-8535
DOI: 10.1186/cc8869